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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
10.91
Human Site:
S529
Identified Species:
21.82
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
S529
K
E
S
E
S
K
K
S
R
P
T
S
K
R
D
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
S529
K
E
S
E
S
K
K
S
R
P
T
S
K
R
D
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
S529
K
E
S
E
S
K
K
S
K
P
T
S
K
R
D
Dog
Lupus familis
XP_536259
1145
128125
R526
K
K
E
S
E
S
K
R
S
R
L
T
P
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
K526
K
K
E
S
E
S
K
K
C
K
L
T
L
L
K
Rat
Rattus norvegicus
NP_445999
1131
125770
K524
K
R
E
L
E
P
K
K
S
K
L
T
P
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
K612
R
K
E
S
G
S
K
K
G
K
W
T
P
E
E
Chicken
Gallus gallus
NP_001006456
1147
128454
K526
K
R
E
A
D
R
K
K
S
N
H
T
P
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
D425
V
V
G
M
A
W
V
D
K
H
K
P
T
S
I
Honey Bee
Apis mellifera
XP_397246
911
103001
T350
P
Q
K
K
E
Y
D
T
K
D
I
A
L
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
K345
Y
F
D
K
D
Q
I
K
T
M
V
E
Q
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
V300
E
E
D
K
L
W
T
V
K
Y
A
P
T
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
93.3
13.3
N.A.
13.3
13.3
N.A.
6.6
13.3
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
26.6
20
N.A.
33.3
26.6
N.A.
N.A.
N.A.
13.3
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
17
0
9
9
0
9
0
0
0
0
25
% D
% Glu:
9
34
42
25
34
0
0
0
0
0
0
9
0
17
17
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% I
% Lys:
59
25
9
25
0
25
67
42
34
25
9
0
25
9
34
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
25
0
17
17
9
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
9
0
0
0
0
9
0
0
0
25
0
17
34
0
0
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
17
0
0
0
9
0
9
17
9
0
0
0
25
0
% R
% Ser:
0
0
25
25
25
25
0
25
25
0
0
25
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
9
9
0
25
42
17
0
0
% T
% Val:
9
9
0
0
0
0
9
9
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _